The skin is connected to the…gut: How tissue crosstalk may orchestrate oral anaphylaxis

A recent study led by Harvard scientists and published in the journal Immunity, has found that severe food allergies (anaphylaxis) can be exacerbated by cross-communication between multiple cell types in the skin and the intestine. In short, your skin can tell your gut to prepare for action! What are allergies/anaphylaxis? The immune system has the … Continue reading The skin is connected to the…gut: How tissue crosstalk may orchestrate oral anaphylaxis

Gut microbes and the quest for needle-free vaccines

by Luisa Torres A new vaccination method may spare us the needles and the pain,  but it may not work as well in people who are obese or in those whose gut bacteria are different due to antibiotic use, researchers from Cornell University reported last month in the Journal of Science Advances. Although vaccines have saved … Continue reading Gut microbes and the quest for needle-free vaccines

Connection interrupted? How regulatory cells selectively tune down immune responses.

Our immune system constantly protects us from threats originating from both the outside and inside of our bodies. One example of internal threats are autoreactive immune cells, which attack our own tissues. Like powerful machines, the immune system requires regulation. There are checkpoints in every immune response and different immune cells must effectively communicate to … Continue reading Connection interrupted? How regulatory cells selectively tune down immune responses.

The regulatory role of IL-9/IL-9R signaling in memory B cell response

Our body can remember specific pathogens and other foreign substances (antigens) years after the first encounter. B cells, the type of lymphocytes that produce antibodies, are one of the key players for the establishment of this long-term memory. Upon activation, B cells proliferate and give rise to antibody-secreting plasma cells (PCs) or memory B cells … Continue reading The regulatory role of IL-9/IL-9R signaling in memory B cell response