Connection interrupted? How regulatory cells selectively tune down immune responses.

Our immune system constantly protects us from threats originating from both the outside and inside of our bodies. One example of internal threats are autoreactive immune cells, which attack our own tissues. Like powerful machines, the immune system requires regulation. There are checkpoints in every immune response and different immune cells must effectively communicate to … Continue reading Connection interrupted? How regulatory cells selectively tune down immune responses.

The regulatory role of IL-9/IL-9R signaling in memory B cell response

Our body can remember specific pathogens and other foreign substances (antigens) years after the first encounter. B cells, the type of lymphocytes that produce antibodies, are one of the key players for the establishment of this long-term memory. Upon activation, B cells proliferate and give rise to antibody-secreting plasma cells (PCs) or memory B cells … Continue reading The regulatory role of IL-9/IL-9R signaling in memory B cell response